Metabolic dysfunction- associated steatohepatitis, or MASH, is an inflammatory, liver-scarring disease that has reached epidemic proportions, with an estimated 1.5% to 6.5% of U.S. adults afflicted by ...

In a bid to gain further understanding of the etiology and pathogenesis of metabolic dysfunction–associated steatohepatitis (MASH), a team of researchers has created 3D bioprinted liver models. MASH, ...

A stained micrograph of 3D primary human liver cell tissue modeling MASH. Areas of fibrosis are indicated in blue. Image courtesy of Viscient Biosciences. Metabolic dysfunction- associated ...

The effectiveness of non-clinical drug safety predictions is enhanced by the adoption of three-dimensional (3D) cellular models. 3D bioprinting enables the generation of complex models with spatial ...

A 3D liver model was engineered by a team of researchers, that accurately replicates the connection between liver cells (hepatocytes) and scarring cells (stellate cells) in the condition of fibrosis.

The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release bile into tiny channels called bile canaliculi, which drain into the bile duct ...

The liver is the body's control tower for metabolism, powering vital functions like converting nutrients to glucose, storing fat and breaking down toxins. Over a third of the world, however, is ...

A US biotechnology company has 3D printed a tiny functioning liver in the lab that survived just over five days -- more than twice the life expectancy of 2D versions. Presenting the results at the ...

Metabolic dysfunction--associated steatohepatitis or MASH (formerly known as nonalcoholic steatohepatitis) is an inflammatory, liver-scarring disease that affects 1.5% to 6.5% of all U.S. adults.