Researchers have engineered a next-generation glutamate sensor, iGluSnFR4, capable of detecting the faintest incoming ...

Parkinson's and Alzheimer's diseases are the two most common neurodegenerative disorders, affecting millions of people worldwide. Published in the Journal of Neuroscience, new research from the ...

Synaptic transmission is an energy hog. It requires neurons to tap ATP reserves to respond to incoming signals. How do they pull this off, thousands to millions of times per day? A new study ...

Researchers from The University of Texas at Dallas’ Center for Advanced Pain Studies (TX, USA) and their colleagues have made a fundamental discovery about a key mechanism that enables nervous system ...

Synaptic pruning is a crucial neurodevelopmental process through which the brain refines its neural circuitry by systematically eliminating excess or weak synaptic connections. During early childhood ...

Increased levels of bioactive lipids produced naturally in the body, which affect excitatory transmission between brain cells, promote mental disorders. However, this mechanism can be rebalanced by ...