Kickoff from Soldier Field is set for 4:25 p.m. ET. The Bears are 4.5-point favorites in the latest Lions vs. Bears odds at DraftKings, and the total is 51.5. Before making any Bears vs. Lions picks of your own, make sure to look at the top NFL picks from the SportsLine Projection Model, which simulates every NFL game 10,000 times.

Following Sunday’s slate, the NFL released its Week 18 schedule, which immediately drew scrutiny. The league announced a Saturday doubleheader featuring the Carolina Panthers vs Tampa Bay Buccaneers at 4:30 p.m. ET and Seahawks-49ers at 8 p.m. ET, followed by a Sunday schedule that culminates with Ravens-Steelers on "SNF."

The Los Angeles Chargers face the Denver Broncos in Week 18 of the NFL season on Sunday at Empower Field at Mile High.

The SportsLine Projection Model is high on the road team. It has the Colts covering the spread in 57% of simulations and winning outright in 34% to bring value as +455 underdogs. The model has the Over hitting in 65% of simulations.

Two playoff spots and the two No. 1 seeds will be decided on the NFL’s final weekend of the regular season, along with four division winners and other seeding issues.