The story of the cell cycle is often told only through the perspective of the chromosomes as they replicate and then divide. This resource beautifully illustrates the role of the cytoskeleton in that ...
The journey started with an enigma in the zebrafish embryo: some endothelial cells, actively involved in the initial stages of the development of the earliest blood vessels, were dividing in an ...
For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process can lead to cell death or diseases like cancer. A new study has shown how ...
Researchers discovered that a long-misunderstood protein plays a key role in helping chromosomes latch onto the right “tracks” during cell division. Instead of acting like a motor, it works more like ...
Researchers have revealed a surprising new role for a key protein in cell division. The discovery, reported in two back-to-back papers, challenges long-standing models and textbook accounts in biology ...
CAPTION: (Top) Condensins seem to act as a molecular crosslinkers to make loops. (Bottom, left) Condensins (red) locate around chromosome center. (Bottom, right) Nucleosomes around the periphery ...
About 100 cells divide every second in our body. A key protein in cell division is a protein kinase termed Plk1, because it activates other proteins involved in this process. Plk1 is also ...
Scientists at the Ruđer Bošković Institute (RBI) in Zagreb, Croatia, have discovered that the protein CENP-E, long believed to act as a motor dragging chromosomes into place during cell division, in ...
Imagine if our bodies could grow new organs throughout our entire lives. Plants do this constantly, thanks to tiny, powerful reservoirs of stem cells. But how do these cells know when to divide, and ...
New findings could aid future development of more efficient therapeutic strategies in the context of regenerative medicine and aging.