One of the most challenging moments in cancer treatment comes when a therapy stops working. In many metastatic cancers, drugs ...

A new study headed by teams at the Wellcome Sanger Institute, EMBL’s European Bioinformatics Institute (EMBL-EBI), and Open Targets has indicated how mutations that cause cancer drug resistance fall ...

On August 8, 2025, the FDA granted accelerated approval to zongertinib for adult patients with unresectable or metastatic ...

An artificial intelligence model was shown to predict tumor mutation burden in lung cancer and other diseases. GigaPath, an artificial intelligence (AI) model, may predict cancer mutations including ...

Dr. Marwan G. Fakih explains that KRAS mutations, found in 45% of patients with colorectal cancer, include the rare KRAS G12C mutation, leading to Lumakras approval. According to the National Cancer ...

Every cancer carries a unique genetic fingerprint: variations in DNA known as “somatic variants” that occur in tumor DNA but are absent from the patient’s healthy cells. While some cancers may also ...

How bladder cancer originates and progresses has been illuminated as never before. Researchers found that antiviral enzymes that mutate the DNA of normal and cancer cells are key promoters of early ...

The gene p53 acts as a tumor suppressor and often is called the ‘guardian of the genome.’ This gene is central to maintaining genomic stability, which prevents mutations from accumulating and leading ...

Doctors are seeing colon cancer in people in their 20s and 30s. New research suggests it starts in infancy.

A lung cancer diagnosis can feel frightening. And when a family member is diagnosed, you might wonder about your own risk, prompting you to ask if lung cancer is hereditary. Smoking tobacco accounts ...