New research reveals a reciprocal regulation between the CFTR chloride channel, implicated in cystic fibrosis, and several members of the SLC26 family of chloride-bicarbonate exchangers. These ...

Fun biology fact: your body can even produce its own sodium bicarbonate, via the pancreas, but when acid levels rise too high, the pancreas can’t keep up, which is why a timely supplement of exogenous ...

Mammalian sperm require activation within the female reproductive tract to fertilize eggs, and bicarbonate is essential for this process in vitro. A recent study implicates the cystic fibrosis ...